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GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0822-YF2304 Anti-Human GPC3 (XW-464) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-464 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2305 Anti-Human GPC3 (XW-465) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-465 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2306 Anti-Human GPC3 (XW-466) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-466 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2307 Anti-Human GPC3 (XW-467) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-467 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2308 Anti-Human GPC3 (XW-468) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-468 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2309 Anti-Human GPC3 (XW-469) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-469 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2310 Anti-Human GPC3 (XW-470) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-470 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2311 Anti-Human GPC3 (XW-471) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-471 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2312 Anti-Human GPC3 (XW-472) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-472 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2313 Anti-Human GPC3 (XW-473) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-473 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2314 Anti-Mouse GPC3 (XW-474) m(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Mouse XW-474 Human scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2315 Anti-Human GPC3 (XW-475) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-475 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2316 Anti-Human GPC3 (XW-476) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-476 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2317 Anti-Human GPC3 (XW-477) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-477 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2318 Anti-Human GPC3 (XW-478) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-478 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2319 Anti-Human GPC3 (XW-479) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-479 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2320 Anti-Human GPC3 (XW-480) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-480 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF8592 TS-Fluc Anti-Human GPC3 scFv (XW-479) CD28-CD3ζ CAR, pCDCAR1 Human XW-479 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8987 TS-Fluc Anti-Human GPC3 scFv (XW-465) 41BB-CD3ζ CAR, pCDCAR1 Human XW-465 Human 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8988 TS-Fluc Anti-Human GPC3 scFv (XW-466) 41BB-CD3ζ CAR, pCDCAR1 Human XW-466 Human 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0823-LX63 Anti-hGPC3 (Ab) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human Ab Adenoviral vectors   Add to Cart   Datasheet
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