L1 cell adhesion molecule(L1-CAM)

L1 cell adhesion molecule(L1-CAM), also known as L1, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1, is encoded by the L1CAM gene, which is a transmembrane protein member of the L1 protein family. By the expression in neural, hematopoietic and transformed epithelial cells, this neuronal cell adhesion molecule playing a role in cell migration, adhesion, neurite outgrowth, myelination and neuronal differentiation. L1-CAM expression promotes invasiveness of the tumor as well as chemoresistance, which is related to ovarian cancer, colon cancer, glioma, renal cell cancer, neuroblastoma, endometrial cancer, melanoma, pancreatic cancer.

Associated Disease
Anti-L1 cell adhesion molecule(L1-CAM) CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-MZ195 T cell First CE7 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ196 T cell Second CE7 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ197 T cell Second CE7 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
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