MAGE-A1

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Associated Disease
Anti-MAGE-A1 TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C115Z Human MZ2-82/30 Human ~8kb Lentiviral EADPTGHSY Non-modified HLA-A*0101 Inquiry
TCR-L236 Human 1367hc Human ~8kb Lentiviral aa 278-286 Non-modified HLA-A2 Inquiry
TCR-L237 Human 1367mc Murinized ~8kb Lentiviral aa 278-286 Murinized HLA-A2 Inquiry
TCR-L238 Human 1367mmc Murinized ~8kb Lentiviral aa 278-286 Minimal murinized HLA-A2 Inquiry
TCR-L239 Human 1405hc Human ~8kb Lentiviral aa 278-286 Non-modified HLA-A2 Inquiry
TCR-L240 Human 1405mc Murinized ~8kb Lentiviral aa 278-286 Murinized HLA-A2 Inquiry
TCR-L241 Human 1405mmc Murinized ~8kb Lentiviral aa 278-286 Minimal murinized HLA-A2 Inquiry
TCR-L242 Human 1705hc Human ~8kb Lentiviral aa 278-286 Non-modified HLA-A2 Inquiry
TCR-L243 Human 1705mc Murinized ~8kb Lentiviral aa 278-286 Murinized HLA-A2 Inquiry
TCR-L244 Human 1705mmc Murinized ~8kb Lentiviral aa 278-286 Minimal murinized HLA-A2 Inquiry
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