MAGE-A4

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Associated Disease
  • Esophageal cancer
Anti-MAGE-A4 TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C131Z Human 2-28 Human ~8kb Lentiviral NYKRCFPVI Codon optimized HLA-A*2402 Inquiry
TCR-L062Z Human Human 8kb Lentiviral NYKRCFPVI Non-modified HLA-A2 Inquiry
TCR-L063 Human Human 6000bp retroviral vector NYKRCFPVI Non-modified TCR HLA-A2 Inquiry
TCR-L394 Human 2-28 Human ~8kb Lentiviral aa 143-151 Non-modified HLA-A24 Inquiry
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