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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-YF005 | Anti-MART-1 (M1) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | M1 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF006 | Anti-MART-1 (M1) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | M1 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF007 | Anti-MART-1 (M7) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | M7 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF008 | Anti-MART-1 (M7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | M7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP072 | Anti-MART-1 (ECD) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | ECD | Rat | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP073 | Anti-MART-1 (ECD) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | ECD | Rat | scFv-CD28-CD3ζ | Lentiviral vector | T cell |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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