Mesothelin

Mesothelin also called MSLN is encoded by MSLN, which is a tumor differentiation antigen that is normally present on the mesothelial cells lining the pleura, peritoneum and pericardium. The limited mesothelin expression in normal tissues and high expression in many cancers makes it an attractive candidate for therapy. Mesothelin not only is related to mesothelioma, ovarian cancer, pancreatic cancer and lung cancer but also is associated with squamous cell carcinomas such as cervix, lung and head and neck carcinomas and adenocarcinomas.

Associated Disease
Anti-Mesothelin CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC023 T cell First m912 ~8kb Retroviral scFv-CD3ζ Human Inquiry
CAR-LC024 T cell Second m912 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC037 T cell Second SS1 ~8kb Lentiviral scFv-ICOS-CD3ζ Mouse Inquiry
CAR-LC053 T cell Second HN1 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC054 T cell Third HN1 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC066 T cell Second M1 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC067 T cell Second M2 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC068 T cell Second M3 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC069 T cell Second M4 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC070 T cell Second M5 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC071 T cell Second M6 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC072 T cell Second M7 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC073 T cell Second M8 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC074 T cell Second M9 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC075 T cell Second M10 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC076 T cell Second M11 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC077 T cell Second M12 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC078 T cell Second M13 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC079 T cell Second M14 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC080 T cell Second M15 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC081 T cell Second M16 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC082 T cell Second M17 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC083 T cell Second M18 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC084 T cell Second M19 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC085 T cell Second M20 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC086 T cell Second M21 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC087 T cell Second M22 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC088 T cell Second M23 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC089 T cell Second M24 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC176 T cell First P4 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-LC177 T cell Second P4 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC268 T cell Second HN1 ~8kb Lentiviral scFv-41BB-FKBP/41BB-FRB-CD3ζ Human Inquiry
CAR-LC269 T cell Second SS1 ~8kb Lentiviral scFv-41BB-FKBP/41BB-FRB-CD3ζ Mouse Inquiry
CAR-LC270 T cell Second m912 ~8kb Lentiviral scFv-41BB-FKBP/41BB-FRB-CD3ζ Human Inquiry
CAR-LC370 T cell Second SS1 ~8kb Lentiviral scFv-KIR2DS2 Mouse Inquiry
CAR-T-1-M321-2 T cell First SS1 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M321-G T cell First SS1 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M321-Z T cell First SS1 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-M321-2G T cell Second SS1 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M321-2Z T cell Second SS1 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M321-4G T cell Second SS1 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M321-8Z T cell Second SS1 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M321-BZ T cell Second SS1 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M321-CZ T cell Second SS1 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-M321-2BZ T cell Third SS1 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M321-2XZ T cell Third SS1 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON