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The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-T-1-M323-Z | Anti-NY-ESO-1 scFv h(CD3ζ) CART, pCDCAR1 | Human | ES121 | Mouse | scFv-CD3ζ | Lentiviral | T cell | ||
| XS-0622-ZP3304 | Anti-NY-ESO-1 h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 | Human | VHH1-VHH2-CD28-CD3ζ | Lentiviral vector | T Cell | ||||
| XS-0622-ZP3476 | Anti-NY-ESO-1 h(VHH1-VHH2-4-1BB-CD3ζ) Biepitopic CAR, pCDCAR1 | VHH1-VHH2-4-1BB-CD3ζ | Lentiviral vector | T Cell | |||||
| XS-0822-YF300 | Anti-Human NY-ESO-1 (XW-300) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-300 | Mouse | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1220 | Anti-Human NY-ESO-1 (XW-300) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-300 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2140 | Anti-Human NY-ESO-1 (XW-300) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-300 | Mouse | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0922-ZP972 | Anti-NY-ESO-1 (2D2) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 2D2 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0922-ZP1282 | Anti-NY-ESO-1 (2D2) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 2D2 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-1122-YF300 | Anti-NY-ESO-1 KIR CAR (scFv-KIR2DS2-DAP12, XW-300), pCDCAR1 | Human | XW-300 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF1220 | Anti-NY-ESO-1 TCR-ABR (scFv-TCRα, XW-300) CAR Plasmid, pCDCAR1 | Human | XW-300 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF2140 | Anti-NY-ESO-1 TCR-ABR (scFv-TCRβ, XW-300) CAR Plasmid, pCDCAR1 | Human | XW-300 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF3060 | Anti-NY-ESO-1 TCR-ABR (scFv-CD3γ, XW-300) CAR Plasmid, pCDCAR1 | Human | XW-300 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3980 | Anti-NY-ESO-1 TCR-ABR (scFv-CD3δ, XW-300) CAR Plasmid, pCDCAR1 | Human | XW-300 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4900 | Anti-NY-ESO-1 TCR-ABR (scFv-CD3ε, XW-300) CAR Plasmid, pCDCAR1 | Human | XW-300 | Mouse | scFv-CD3ε | Lentiviral vector | T Cell | ||
| XS-1122-YF5820 | Anti-NY-ESO-1 (XW-300) h(CD28-CD3ζ) CAR, pAAV | Human | XW-300 | Mouse | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF6740 | Anti-NY-ESO-1 (XW-300) h(41BB-CD3ζ) CAR, pAAV | Human | XW-300 | Mouse | scFv-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF7660 | Anti-NY-ESO-1 (XW-300) h(CD28-41BB-CD3ζ) CAR, pAAV | Human | XW-300 | Mouse | scFv-CD28-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-0123-ZP625 | Anti-NY-ESO-1 (2D2) h(scFv-CD3ε) TRuC, pCDTRC1 | Human | 2D2 | Mouse | scFv-CD3ε | Lentiviral vector | T cell | ||
| XS-0323-ZP625 | Anti-NY-ESO-1 (2D2 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 2D2 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0923-LX49 | Anti-hNY-ESO-1 (CD28-41BB-CD3ζ) CAR-duplex CTLA4 pCDCAR1 Vector | Human | X9X-18 | scFv-CD28-41BB-CD3ζ-duplex CTLA4 | Lentiviral vector | T cell | CAR-T |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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