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TAG-72

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Tumor-associated glycoprotein 72 (TAG-72), also known as CA72-4, is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, lung, and pancreatic cancers. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment. TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.

Associated Disease
  • Colon cancer
  • Colorectal cancer
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-T-1-M551-G Anti-TAG-72 VHH h(FcεRIγ) CAR, [T] Human CC49 Humanized VHH-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-ZP142 Anti-TAG-72 (huCC49) h(CD28-CD3ζ) CAR, pCDCAR1 Human huCC49 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP143 Anti-TAG-72 (huCC49) h(41BB-CD3ζ) CAR, pCDCAR1 Human huCC49 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5895 Anti-TAG-72 (Anatumomab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Anatumomab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5896 Anti-TAG-72 (Anatumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Anatumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5908 Anti-TAG-72 (Satumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Satumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5909 Anti-TAG-72 (Minretumomab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Minretumomab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5910 Anti-TAG-72 (Minretumomab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Minretumomab Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5911 Anti-TAG-72 (TKH6) h(CD28-CD3ζ) CAR, pCDCAR1 Human TKH6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-YF1753 Anti-Human TAG-72 (XW-833) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-833 Mouse scFv-CD28-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF2673 Anti-Human TAG-72 (XW-833) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-833 Mouse scFv-CD28-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-1122-YF833 Anti-TAG-72 KIR CAR (scFv-KIR2DS2-DAP12, XW-833), pCDCAR1 Human XW-833 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1753 Anti-TAG-72 TCR-ABR (scFv-TCRα, XW-833) CAR Plasmid, pCDCAR1 Human XW-833 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2673 Anti-TAG-72 TCR-ABR (scFv-TCRβ, XW-833) CAR Plasmid, pCDCAR1 Human XW-833 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF3593 Anti-TAG-72 TCR-ABR (scFv-CD3γ, XW-833) CAR Plasmid, pCDCAR1 Human XW-833 Mouse scFv-CD3γ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF4513 Anti-TAG-72 TCR-ABR (scFv-CD3δ, XW-833) CAR Plasmid, pCDCAR1 Human XW-833 Mouse scFv-CD3δ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF5433 Anti-TAG-72 TCR-ABR (scFv-CD3ε, XW-833) CAR Plasmid, pCDCAR1 Human XW-833 Mouse scFv-CD3ε Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF6353 Anti-TAG-72 (XW-833) h(CD28-CD3ζ) CAR, pAAV Human XW-833 Mouse scFv-CD28-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF7273 Anti-TAG-72 (XW-833) h(41BB-CD3ζ) CAR, pAAV Human XW-833 Mouse scFv-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
XS-1122-YF8193 Anti-TAG-72 (XW-833) h(CD28-41BB-CD3ζ) CAR, pAAV Human XW-833 Mouse scFv-CD28-41BB-CD3ζ Adeno-associated viral (AAV) vector T Cell   Add to Cart   Datasheet
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