TSLPR (Thymic stromal lymphopoietin protein receptor) is known as the cytokine receptor-like 2, CRL2 and IL-XR, which belongs to the type I cytokine receptor family. It is expressed mainly in myeloid cells, dendritic cells and activated monocytes. Also, TSLPR is weekly expressed in T cells. TSLPR is associated with acute lymphobiastic leukemia (ALL). Combined with the interleukin 7receptor (IL7R), TSLPR activate the pathways of STAT3, STAT5 and JAK2, which is regulated the processes of proliferation and development of the hematopoietic system.
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