VEGFR-2

Vascular endothelial growth factor receptor 2 (VEGFR2) is a primary responder to vascular endothelial growth factor signal, and thereby regulates endothelial migration and proliferation. This receptor is expressed in endothelial cells and some vascular tumors, but many reports also detail its expression in carcinomas and lymphomas. VEGFR2 is a potential cell type marker, and data on VEGFR2 expression may also have therapeutic significance in view of recent availability of VEGFR2 inhibitors. As it directly upregulates tumor angiogenesis, VEGFR-2 is an appropriate target for suppression of solid tumor growth using exogenous antibodies, small inhibitory molecules and in vivo stimulation of the immune system.

Associated Disease
Anti-VEGFR-2 CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC132 T cell Third KDR-1121 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC133 T cell Second KDR-1121 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-1-L341-2 T cell First DC101 8kb Lentiviral scFv-CD28 Rat Inquiry
CAR-T-1-L341-G T cell First DC101 8kb Lentiviral scFv-FcεRIγ Rat Inquiry
CAR-T-1-L341-Z T cell First DC101 8kb Lentiviral scFv-CD3ζ Rat Inquiry
CAR-T-2-L341-2G T cell Second DC101 8kb Lentiviral scFv-CD28-FcεRIγ Rat Inquiry
CAR-T-2-L341-2Z T cell Second DC101 8kb Lentiviral scFv-CD28-CD3ζ Rat Inquiry
CAR-T-2-L341-4G T cell Second DC101 8kb Lentiviral scFv-CD4-FcεRIγ Rat Inquiry
CAR-T-2-L341-4Z T cell Second DC101 8kb Lentiviral scFv-CD4-CD3ζ Rat Inquiry
CAR-T-2-L341-8Z T cell Second DC101 8kb Lentiviral scFv-CD8-CD3ζ Rat Inquiry
CAR-T-2-L341-BZ T cell Second DC101 8kb Lentiviral scFv-41BB-CD3ζ Rat Inquiry
CAR-T-2-L341-CZ T cell Second DC101 8kb Lentiviral scFv-b2c-CD3ζ Rat Inquiry
CAR-T-3-L341-2BZ T cell Third DC101 8kb Lentiviral scFv-CD28-41BB-CD3ζ Rat Inquiry
CAR-T-3-L341-2XZ T cell Third DC101 8kb Lentiviral scFv-CD28-OX40-CD3ζ Rat Inquiry
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Tel: 1-631-871-5806
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Email:

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Tel: 44-207-097-1828

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