| Cat. No. |
CRP0841 |
| Product Overview |
Recombinant
Mycoplasma Hominis Arginine Deiminase produced in E. coli has a
molecular mass of 46,260 Da. |
| Description |
Arginine
deiminase is a ~46 kDa protein that was isolated from the
mycoplasma-contaminated cell culture. ADI can degrade arginine
to citrulline and NHB3B. rADI has acted as a potent inhibitor of
the growth of some arginine-dependent tumor in vitro and in
vivo. rADI is expressed in E. coli and purified via Q-sepharose
column. |
| background |
This gene is a
member of a gene family which encodes enzymes responsible for
the conversion of arginine residues to citrulline residues. This
gene may play a role in granulocyte and macrophage development
leading to inflammation and immune response. |
| synonyms |
L-arginine
iminohydrolase;arginine dihydrolase;citrulline iminase; L-arginine
deiminase |
| Purity |
≥95% as
determined by SDS-PAGE. |
| PI |
5.5 by
Isoelectricfocusing |
| Component |
r-ADI, PBS
buffer, pH 7.4 |
| Specific Activity |
19 U/mg by G-cell
Kit. The activity is assayed on anti-tumor cell in vitro. |
| Endotoxin |
less than 10EU/mg
as determined by LAL method |
| Concentration |
2 mg / ml by BCA
|
| Storage Buffer
|
Liquid in PBS
Buffer. |
| Storage |
At 4℃ for 6
months and -80℃ for 2 years |
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