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     SDF-1α

          Stromal Cell-Dreived Factor 1α                                  [back]                                                     PRICE INQUIRY
 Cat. No.

CRP0858

 Product overview

Recombinant Human Stromal Cell-Dreived Factor 1α produced in E. coli has a molecular mass of approximately 8 KDa.

 Description

SDF-1α, a member of the chemokine α subfamily, chemottracts with T-lymphocytes, monocytes, pro-and pre-B cells, but not neutrophils. It is highly conserved between species with one amino acid substitution between human and mouse. Recombinant stromal cell-dreived factor 1α is expressed in E. coli.

 Purity

>95% as determined by HPLC.

 Specific Activity

Measured by its ability to chemoattract cultured human macrovascular endothelial cells.

 Storage buffer

Liquid. In PBS Buffer.

 Gene Information

 

Gene Name

CXCL12

Synonyms

PBSF; SCYB12; SDF-1a; SDF-1b; SDF1; SDF-1; SDF1A; SDF1B; TLSF; TLSF-a; TLSF-b; TPAR1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; Stromal cell-derived factor 1 precursor; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); stromal cell-derived factor 1; stromal cell-derived factor 1 delta; stromal cell-derived factor 1 gamma; stromal cell-derived factor 1a

GeneID

6387

mRNA Refseq

NM_199168.2

Protein Refseq

NP_954637.1

MIM

600835   

Uniprot ID

P48061

Chromosome Location

10q11.1

Pathway

Axon guidance,  Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration   

Function

chemokine activity, chemokine activity, growth factor activity, signal transducer activity

 
Crystal structure of SDF-1α

 Download Datasheet

PDB rendering based on 1a15.