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     TPC1808 (Rat)

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 Cat. No.

CRP08133

 Product Overview

Recombinant Rat Tropic 1808 produced in E.coli is a single non-glycosylated polypeptide chain containing 285 amino acids and having a molecular mass of approximately 29.1 kDa.

 Description

Rat Tropic 1808 is a candidate chemotropic factor induced by nerve injury. Tpc1808 protein, similar to NGF, could promote the expression of NF-H in a time-dependent manner. Tpc1808 is the gene related to promotion of nerve growth, and both the Tpc1808 gene and the Tpc1808 recombinant protein up-regulate the expression of NF-H in PC12 cells.

 Purity

>95% by SDS-PAGE and HPLC analyses.

 Formulation

Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 1×PBS, pH 7.4.

 Endotoxin

Less than 1EU/μg of rRaTPC1808 as determined by LAL method.

 Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

 Storage

This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

 Gene Information

 

Gene Name

Tpc1808

Synonyms

tropic 1808

GeneID

64560

mRNA Refseq

NM_022625

Protein Refseq

NP_072147

Function

amidase activity

 
 

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