| Cat. No. |
CRP0863 |
| Product overview |
Recombinant Human
Voltage Dependent Anion Channel-1 produced in E. coli has a
molecular mass of approximately 32 KDa. |
| Description |
VDAC forms a
channel through the mitochondrial outer membrane and also the
plasma membrane. The channel allows diffusion of small
hydrophilic molecules; it adopts an open conformation at low or
zero membrane potential and a closed conformation at potentials
above 30-40 mV. The open state has weak anion selectivity
whereas the closed state is cation-selective. rh-VDAC is
expressed in E. coli. |
| Purity |
≥ 95% by
SDS-PAGE. |
| Storage buffer |
Liquid. In 1%
Acetic Acid. |
| Gene
Information |
Gene Name |
VDAC1 |
|
Synonyms |
MGC111064; PORIN;
PORIN-31-HL; VDAC; VDAC-1; hVDAC1; Outer mitochondrial membrane
protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM;
Voltage-dependent anion-selective channel protein 1;
voltage-dependent anion channel 1 |
|
GeneID |
7416 |
|
mRNA Refseq |
NM_003374.1 |
|
Protein Refseq |
NP_003365.1 |
|
MIM |
604492 |
|
Uniprot ID |
P21796 |
|
Chromosome Location |
5q31 |
|
Pathway |
Calcium signaling
pathway |
|
Function |
protein
binding.voltage-gated anion channel activity |
|
Process |
anion transport.
apoptotic program. interspecies interaction between organisms |
|
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