Cat. No.

CRP0861

 Product Overview

Recombinant Human Soluble Tissue Factor produced in E. coli has a molecular mass of 24.8 Da.

 Description

Tissue factor is a cell-surface protein of endothelial cells and monocytes involved in coagulation and inflammation. It is the primary cellular initiator of coagulation cascade, and functions as receptor and cofactor for coagulation Factor VII and VIIa. Soluble human tissue factor with a histidine-tagged extracelullar domain is expressed in E. coli.

 Purity

≥95% as determined by SDS-PAGE.

 Component

Tissue factor, PBS buffer, pH 7.4

 PI

5.16 by Isoelectricfocusing

 concentration

2 mg / ml by BCA

 Specific Activity

The activity is similar as that of full-length tissue factor using clotting assay.

 Endotoxin

less than 10EU/mg as determined by LAL method

 Storage Buffer  

Liquid. In PBS Buffer.

 Storage

At 4℃ for 6 months and -80℃ for 2 years

 Gene Information

Gene Name

F3

Synonyms

CD142; TF; TFAD; TFA; Thromboplastin; CD142 antigen; Coagulation factor III; Tissue factor precursor; coagulation factor III (thromboplastin, tissue factor); tissue factor,TF_HUMAN. 

GeneID

2152

mRNA Refseq

NM_001993

Protein Refseq

NP_001984

MIM

134390  

UniProt ID

P13726

Chromosome Location

1p22-p21 

process

blood coagulation, blood coagulation, extrinsic pathway