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Cancer-On-A-Chip Kit (CAT#: DBFF1-HX2)

Datasheet

Overview

Cancer-On-A-Chip is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically and morphologically realistic tumor microenvironment. The system enables (a) circulation in the microvasculature, (b) transport across the vessel walls, and (c) delivery to the tumors. Starting with scans of vascular networks incorporated with interstitial and tissue/tumor spaces, the 3D tumor tissue model creates an in-vitro tumor microenvironment akin to a viable histological slice.

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Product overview

Product Overview
Cancer-On-A-Chip is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically and morphologically realistic tumor microenvironment. The system enables (a) circulation in the microvasculature, (b) transport across the vessel walls, and (c) delivery to the tumors. Starting with scans of vascular networks incorporated with interstitial and tissue/tumor spaces, the 3D tumor tissue model creates an in-vitro tumor microenvironment akin to a viable histological slice.
Product Type
3D modeling kits
Components
Starter Kit:
10 chips (Choice of IMN2 radial, IMN2 linear or SMN2 microvascular network chips)
Accessories including tubing, clamps, needles, and syringes
Pneumatic priming device (required for priming tubing to remove air)

Assay Kit:
10 chips (Choice of IMN2 radial, IMN2 linear or SMN2 microvascular network chips)
Accessories including tubing, clamps, needles, and syringes

Product applications

Applications
Suitable for various studies, such as efficacy and toxicity screening, tumor-induced vascular leakage, tumor intravasation and extravasation, tumor immune interactions, and biomarker analysis.

Product quality

Features
Quantitative real-time visualization
Physiological leaky vasculature
Morphologically realistic architecture
Realistic convective and diffusive transport

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For Research Use Only | Not For Clinical Use

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