3D Ex Vivo Human Genitourinary Tissue Model Introduction

Creative Biolabs proudly provides innovative 3D ex vivo human genitourinary system tissue model, a cutting-edge biotechnology tool to help advance the understanding and treatment of human diseases.

Genitourinary System and Related Diseases

The human genitourinary system, which includes the ovary, cervix, prostate, fallopian tubes, etc. is essential for maintaining homeostasis and eliminating waste from the body. With the prevalence of genitourinary system-related diseases such as prostate cancer, urinary tract infections, and infertility, the patient's quality of life is severely reduced and, in severe cases, even death. The pathogenic mechanisms underlying genitourinary system-related diseases are multifaceted, involving a variety of genetic, environmental, and lifestyle factors.

Fig 1. Hematoxylin and eosin-stained sections of prostate specimen.Fig 1. Complete sampling with the whole-mount technique of a prostate specimen.1,3

Traditional Models for Genitourinary System

Existing cellular models also encounter challenges in accurately replicating essential structures and physiological characteristics, especially in the genitourinary tracts where structural integrity is paramount. Although large animal models provide better insights into human anatomy and surgical procedures, the morphology and tissue properties of animal organs differ from those of the human body. Furthermore, animal models often exhibit substantial variations that quickly deteriorate after induction. Moreover, the construction of large animal organ models is financially burdensome and raises ethical concerns.

Fig 2. Precision cut tissue slices derived from radical prostatectomy or a patient-derived xenograft.Fig 2. Tissue slice culture workflow and preclinical endpoints.2,3

3D Ex Vivo Human Genitourinary System Tissue Model at Creative Biolabs

Creative Biolabs specializes in providing state-of-the-art 3D ex vivo human genitourinary system tissue models for global researchers. This innovative model represents a substantial leap forward compared to conventional models, revolutionizing the study of genitourinary system-related diseases. Researchers and drug developers now have a reliable and ethical platform to test potential treatments with greater confidence.

By offering this cutting-edge model, our primary objective is to introduce novel avenues for genitourinary system research while simultaneously reducing reliance on animal models. This advancement significantly enhances the credibility of biomedical research by bridging the gap between preclinical studies and clinical applications. Our model not only enables a deeper understanding of genitourinary system diseases but also accelerates the development of effective therapeutic strategies.

What Do We Provide?

We appreciate your interest in our research models for the genitourinary system. With years of experience and advanced platform, we offer a diverse range of models designed to meet various research needs and objectives. Here are some of our notable models that you can choose from:

Creative Biolabs is committed to driving scientific progress and facilitating breakthrough discoveries in the realm of genitourinary system research. By minimizing the need for animal usage, we uphold the principles of ethical research while providing a robust foundation for high-quality studies. Our ultimate goal is to enhance your research in the fields of human health, disease modeling, drug screening, and precision medicine. Please feel free to contact us to discuss your specific research needs and explore how our expertise and resources can contribute to your success.

References

  1. Montironi, R.; et al. Handling of radical prostatectomy specimens: total embedding with large-format histology. Int J Breast Cancer. 2012, 932784.
  2. Perez, L.; et al. Harnessing the utility of ex vivo patient prostate tissue slice cultures. Front Oncol. 2022, 12: 864723.
  3. Distributed under Open Access License CC BY 4.0, without modification.
Research Model

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