3D Ex Vivo Human Prostate Tissue Model Introduction

Creative Biolabs provides 3D ex vivo human fallopian tube tissue model to facilitate research and precision interventions for female reproductive disorders of relevance to them.

Introduction to Prostate Tissue

3D Ex Vivo Human Prostate Tissue Model

• The lumenal structure of the prostate gland in vivo is consistent with the lumenal structure of the prostate gland, and the outer layer specifically expresses markers CK5 and p63, and the inner layer expresses marker CK8.
• Exhibits genetic characteristics of primary tissues, including p53 status, hormone receptor status, and microsatellite instability phenotypes, and can be amplified indefinitely in culture in vitro.
• Maintains the characteristics of tumor cells in vivo in various aspects such as gene copy number changes in the genome, mutation mapping, and histomorphological features.
• Direct and rapid amplification from diseased cells facilitates the development of prostate cancer model biobanks and personalized therapy.

Fig 1. Schematic outline of PDCO culture processes.¹

Fig 2. Characterization of prostate cancer cell lines in 3D micro-tumor culture.²

Other Models of Potential Interest

• 3D Ex Vivo Human Uterine Contractility Model
• 3D Ex Vivo Human Uterine Relaxation Model
• 3D Ex Vivo Human Vagina Tissue Model
• 3D Ex Vivo Human Ovary Tissue Model
• 3D Ex Vivo Human Breast Tissue Model
• 3D Ex Vivo Human Cervix Tissue Model
• 3D Ex Vivo Human Fallopian Tube Tissue Model

Creative Biolabs has developed the 3D ex vivo human prostate tissue model to help customers solve the problem of model building for prostate-related research and greatly contributed to the elucidation of the mechanisms of cell lineage fate transition in prostate related diseases. Please contact us to obtain models to assist in your prostate research.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model