yttrium (90Y) tacatuzumab tetraxetan
DESCRIPTION |
CATALOG # |
SIZE |
PRICE |
Anti-AFP Therapeutic Antibody (AFP-Cide) |
TAB-713 |
1mg |
Please Inquiry |
Product Detail
- Cat
- TAB-713
- Product Overview
- Recombinant humanized (from mouse) antibody expressed in CHO binding to human AFP. Yttrium (90Y) tacatuzumab tetraxetan is a humanized monoclonal antibody intended for the treatment of cancer. The antibody itself, tacatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells.
- Target
- AFP
- Type
- IgG1 - kappa
- Immunogen
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Human
- Expression Host
- CHO
- Applications
- Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, WB and most other immunological methods.
- CAS
- 476413-07-7
- Trade name
- afp-cide
- Molecular Weight
- 145 kDa
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Size
- 1mg
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
- Introduction
- Yttrium (90Y) tacatuzumab tetraxetan is a humanized monoclonal antibody intended for the treatment of cancer.
- Antigen Description
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
- Function
- metal ion binding;
- Gene ID
- 174
- Synonyms
- AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein;
- Download Datasheet:
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