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Recombinant humanized (from mouse) antibody expressed in CHO binding to human AFP. Yttrium (90Y) tacatuzumab tetraxetan is a humanized monoclonal antibody intended for the treatment of cancer. The antibody itself, tacatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, WB and most other immunological methods.
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Yttrium (90Y) tacatuzumab tetraxetan is a humanized monoclonal antibody intended for the treatment of cancer.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.