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Recombinant human monoclonal antibody expressed in CHO binding to human ANGPT2. Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
The details of the immunogen for this antibody are not available.
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
Predicted N terminal
>95.0% as determined by analysis by RP-HPLC.
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding;