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nesvacumab (TAB-769)

DESCRIPTION CATALOG # SIZE PRICE
Anti-ANGPT2 Therapeutic Antibody TAB-769 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant human monoclonal antibody expressed in CHO binding to human ANGPT2. Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
  • Target
  • ANGPT2
  • Type
  • IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
  • CAS
  • 1296818-77-3
  • Predicted N terminal
  • EVQLVESG
  • Molecular Weight
  • 144.9 kDa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Introduction
  • Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
  • Antigen Description
  • The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
  • Function
  • metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding;
  • Synonyms
  • ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; ANG2; AGPT2;

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