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Recombinant chimeric/humanized hybrid (mouse/human) antibody expressed in CHO binding to human CD248. Ontuxizumab is a monoclonal antibody designed for the treatment of cancer.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
Predicted N terminal
>95.0% as determined by analysis by SDS-PAGE.
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Ontuxizumab is a monoclonal antibody designed for the treatment of cancer and binds to TEM1.
Endosialin is a protein that in humans is encoded by the CD248 gene.Endosialin is a member of the "Group XIV", a novel family of C-type lectin transmembrane receptors which play a role not only in cell-cell adhesion processes but also in host defence. This family comprise two other members, CD93 and Thrombomodulin which are better characterized. Even though the function of endosialin remains elusive, its expression has been associated with angiogenesis in the embryo, uterus and in tumor development and growth.
binding; calcium ion binding; molecular_function; sugar binding;