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lintuzumab (TAB-756)

DESCRIPTION CATALOG # SIZE PRICE
Anti-CD33 Therapeutic Antibody (ZAMYL/Smart) TAB-756 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD33. Lintuzumab is a humanized monoclonal antibody used in the treatment of cancer.
  • Target
  • CD33
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • Sp2/0 mouse myeloma cells
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 166089-32-3
  • Trade name
  • zamyl/smart
  • Predicted N terminal
  • QVQLVQSG
  • Molecular Weight
  • 46.96 kDa
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Introduction
  • Lintuzumab (SGN-33) is a humanized monoclonal antibody used in the treatment of cancer.
  • Antigen Description
  • CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage.It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
  • Function
  • receptor activity; sugar binding;
  • Synonyms
  • CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3;

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