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Recombinant humanized (from mouse) antibody Fab fragment expressed in CHO binding to human CFD. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
Fab - G1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF and most other immunological methods.
Predicted N terminal
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.