lampalizumab
DESCRIPTION |
CATALOG # |
SIZE |
PRICE |
Anti-CFD Therapeutic Antibody |
TAB-754 |
1mg |
Please Inquiry |
Product Detail
- Cat
- TAB-754
- Product Overview
- Recombinant humanized (from mouse) antibody Fab fragment expressed in CHO binding to human CFD. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
- Target
- CFD
- Type
- Fab - G1 - kappa
- Immunogen
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Human
- Expression Host
- CHO
- Applications
- Suitable for use in ELISA, IP, FC, FuncS, Neut, IF and most other immunological methods.
- CAS
- 1278466-20-8
- Predicted N terminal
- EVQLVQSG
- Molecular Weight
- 46.96 kDa
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Size
- 1mg
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
- Introduction
- Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
- Antigen Description
- The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
- Function
- peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;
- Gene ID
- 1675
- Synonyms
- CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN;
- Download Datasheet:
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