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Recombinant monoclonal antibody to CMV. Sevirumab (MSL-109) is a human monoclonal antibody for the treatment of infections with cytomegalovirus in patients with AIDS.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
Tested positive against native CMV antigen.
Predicted N terminal
H chain: EEQVLES; L chain: DIVMTQS
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
This is a human monoclonal antibody for the treatment of infections with cytomegalovirus in patients with AIDS.
Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period.
55 kDa immediate-early protein 1; 45 kDa immediate-early protein 2; CMV; Envelope glycoprotein B; gB; Glycoprotein B; HHV 5; HHV5; Human herpesvirus 5; IE1; IE2; UL122; UL122 regulatory protein IE2; UL123; UL123 regulatory protein IE1; UL55; UL55 envelope glycoprotein B