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setoxaximab (TAB-H61)

DESCRIPTION CATALOG # SIZE PRICE
Anti-E. coli Stx2A Therapeutic Antibody TAB-H61 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse antibody to E. coli Stx2
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • E. coli
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
  • CAS
  • 1351470-17-1
  • Specificity
  • shiga toxin type 2 (shiga toxin-producing Escherichia coli (STEC), stx2, Stx2, Stx-2, Shiga-like toxin 2, SLT-2, SLT-II) A subunit [Escherichia coli]
  • Protein Construction
  • gamma1 heavy chain (1-451) [Mus musculus VH (IGHV1-39*01 – (IGHD) – IGHJ1*01) [8.8.12] (1-119)– linker (120-121) – Homo sapiens IGHG1*01 (CH1 (122-219), hinge (220-234), CH2 (235-344), CH3(345-449), CHS (450-451) (122-451)], (224-220') – disulfide withkappa light chain (1'-220') [Mus musculus V-KAPPA (IGKV8-30*01 – IGKJ5*01) [12.3.9] (1'-113') –Homo sapiens IGKC*01 (114'-220')]; dimer (230-230'':233-233'') – bisdisulfide
  • Purity
  • Purity >95% by SDS-PAGE.

BACKGROUND

  • Introduction
  • Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named for Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the shigatoxigenic group of Escherichia coli (STEC), which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC).
  • Keywords
  • Shiga toxin; E. coli Stx2; stx2; Stx2; Stx-2; Shiga-like toxin 2; SLT-2; SLT-II

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