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lumiliximab (TAB-760)

DESCRIPTION CATALOG # SIZE PRICE
Anti-FCER2/CD32 Therapeutic Antibody TAB-760 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant chimeric (primate/human) antibody expressed in CHO binding to human FCER2/CD32. Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
  • Target
  • FCER2/CD32
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • CAS
  • 357613-86-6
  • Molecular Weight
  • 47.75 kDa
  • Purity
  • >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Introduction
  • Lumiliximab is a monoclonal antibody that targets CD23 and acts as an immunomodulator.
  • Antigen Description
  • The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Function
  • IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;
  • Synonyms
  • FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;

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