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Recombinant humanized antibody expressed in CHO binding to human HGF. Ficlatuzumab is a humanized monoclonal antibody designed for the treatment of cancers.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
Predicted N terminal
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Ficlatuzumab is a humanized monoclonal antibody designed for the treatment of cancers.
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. IL-22 is an α-helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1 subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells.
catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;