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Anti-Human ANGPTL3 Therapeutic Antibody (TAB-H30)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ANGPTL3 Therapeutic Antibody TAB-H30 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant human antibody to Human ANGPTL3. mAb targeting angiopoietin-like 3 (ANGPTL3)
  • Type
  • IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • Protein Construction
  • γ4 heavy chain (1-453) [human VH (IGHV3-43*02 (93%) – (IGHD) – IGHJ3*02) [8.8.19] (1-126) – IGHG4*01 H S108>P (234) (127-453)] (140-214')– disulfide withkappa light chain (1'-214') [human V-KAPPA (IGKV1-5*03 (99%) – IGKJ2*01) [6.3.9] (1'-107') – IGKC*01 (108'-214')] dimer (232-232'':235-235'') –bisdisulfide
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.

BACKGROUND

  • Antigen Description
  • ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism. ANGPTL3 monoclonal antibody recognizes the fibrinogen-like domain (FLD) of human ANGPTL3. It detects a band of ~68 kDa and a cleaved band of ~35 kDa by WB. It does not cross-react with other ANGPTL family proteins.
  • Function
  • cell surface binding; enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity;
  • Synonyms
  • ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; ANG-5; FHBL2;

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