Vepalimomab

Cat

TAB-137

Product Overview

Recombinant monoclonal antibody to AOC3. Vepalimomab is a mouse monoclonal antibody developed for the treatment of inflammations. It blocks the vascular adhesion protein 1.

Target

AOC3

Type

IgM

Immunogen

Purified vessels from human peripheral lymph nodes.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.

CAS

195158-85-1

Specificity

Tested positive against native human antigen.

Protein Construction

Immunoglobulin M (mouse monoclonal 1B2 μ-chain anti-human vascular adhesion protein VAP-1), disulfide with mouse monoclonal 1B2light chain, dimer

Purity

Purity >95% by SDS-PAGE.

Size

1mg

Storage

Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Antigen Description

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.

Function

aliphatic-amine oxidase activity; aminoacetone:oxygen oxidoreductase(deaminating) activity; calcium ion binding; cation channel activity; copper ion binding; copper ion binding; oxidoreductase activity; phenethylamine:oxygen oxidoreductase (deaminating) a

Gene ID

8639

Synonyms

AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;

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