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Vepalimomab (TAB-137)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human AOC3 Therapeutic Antibody TAB-137 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to AOC3. Vepalimomab is a mouse monoclonal antibody developed for the treatment of inflammations. It blocks the vascular adhesion protein 1.
  • Target
  • AOC3
  • Type
  • IgM
  • Immunogen
  • Purified vessels from human peripheral lymph nodes.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
  • CAS
  • 195158-85-1
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin M (mouse monoclonal 1B2 μ-chain anti-human vascular adhesion protein VAP-1), disulfide with mouse monoclonal 1B2light chain, dimer
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.
  • Function
  • aliphatic-amine oxidase activity; aminoacetone:oxygen oxidoreductase(deaminating) activity; calcium ion binding; cation channel activity; copper ion binding; copper ion binding; oxidoreductase activity; phenethylamine:oxygen oxidoreductase (deaminating) a
  • Synonyms
  • AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;

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