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Gomiliximab (TAB-231)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD23 Therapeutic Antibody TAB-231 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.
  • Target
  • CD23
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
  • CAS
  • 357613-86-6
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti (human immunoglobulin E receptor type II) (human Macaca irus monoclonal IDEC 152 γ1 chain), disulfide with human Macaca irus monoclonal IDEC 152 kappachain, dimer
  • Molecular Weight
  • 153860
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
  • Function
  • IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;
  • Synonyms
  • FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;

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