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Iratumumab (TAB-144)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD30 Therapeutic Antibody TAB-144 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to CD30. Iratumumab is a human monoclonal antibody used in the treatment of oncological diseases such as relapsed refractory CD30-positive lymphoma including Hodgkin's disease.
  • Target
  • CD30
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • CAS
  • 640735-09-7
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti- (human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer
  • Molecular Weight
  • 170000
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
  • Function
  • binding; receptor activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;
  • Synonyms
  • TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30, D1S166E; tumor necrosis factor receptor superfamily member 8; KI 1; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30; CD30; Ki-1; D1S166E;

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