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Priliximab (TAB-164)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD4 Recombinant Antibody (Centara) TAB-164 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to CD4. Priliximab (cMT 412) is a human-mouse chimeric anti-CD4 monoclonal antibody. It has been tested on patients with Crohn's disease and multiple sclerosis but has not yet received U.S. Food and Drug Administration licencing.
  • Target
  • CD4
  • Type
  • IgG1 - kappa
  • Immunogen
  • P815 mastocytoma ce11stransfected with human CD4 cDNA
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • CAS
  • 147191-91-1
  • Trade name
  • centara
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1,anti-(human CD4 (antigen)) (human-mouse monoclonal cm-T412 g1-chain), disulfide withhuman-mouse monoclonal cm-T412 k-chain, dimer
  • Purity
  • >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

BACKGROUND

  • Antigen Description
  • Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
  • Function
  • MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling re
  • Synonyms
  • CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

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