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Recombinant mouse monoclonal antibody expressed in CHO binding to human CD5. Telimomab aritox is a mouse monoclonal antibody which is an immunosuppressive drug. The antibody is linked to the A chain of the ricin protein.
The details of the immunogen for this antibody are not available.
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
Predicted N terminal
Approximately 150 kDa
>95.0% as determined by analysis by RP-HPLC.
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Telimomab aritox is a mouse monoclonal antibody which is an immunosuppressive drug. The antibody is linked to the A chain of the ricin protein.
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.