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Telimomab aritox (TAB-885)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD5 Therapeutic Antibody TAB-885 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant mouse monoclonal antibody expressed in CHO binding to human CD5. Telimomab aritox is a mouse monoclonal antibody which is an immunosuppressive drug. The antibody is linked to the A chain of the ricin protein.
  • Target
  • CD5
  • Type
  • Fab
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • CAS
  • 117305-33-6
  • Predicted N terminal
  • MPMGSLQP
  • Molecular Weight
  • Approximately 150 kDa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Introduction
  • Telimomab aritox is a mouse monoclonal antibody which is an immunosuppressive drug. The antibody is linked to the A chain of the ricin protein.
  • Antigen Description
  • Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
    The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
  • Function
  • glycoprotein binding; protein binding; receptor activity; scavenger receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • CD5; CD5 molecule; CD5 antigen (p56 62) , LEU1; T-cell surface glycoprotein CD5; T1; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1; LEU1;

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