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Galiximab (TAB-215)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD80 Therapeutic Antibody TAB-215 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to CD8. Galiximab is a monoclonal antibody designed for the treatment of B-cell lymphoma. As of September 2009, The drug is a chimeric antibody from Macaca irus and Homo sapiens.
  • Target
  • CD80
  • Type
  • IgG1 - lambda
  • Immunogen
  • CD80-transfected CHO cell line.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
  • CAS
  • 357613-77-5
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human CD80 (antigen)) (human-Macaca irus monoclonal IDEC-114 heavy chain), disulfide with human- Macaca irus monoclonal IDEC-114 l chain, dimer
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • Function
  • coreceptor activity; protein binding; receptor activity;
  • Synonyms
  • CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B7; BB1; B7-1; LAB7; CD28LG; CD28LG1;

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