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Recombinant monoclonal antibody to CD8. Galiximab is a monoclonal antibody designed for the treatment of B-cell lymphoma. As of September 2009, The drug is a chimeric antibody from Macaca irus and Homo sapiens.
IgG1 - lambda
CD80-transfected CHO cell line.
Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
Tested positive against native human antigen.
Immunoglobulin G1, anti-(human CD80 (antigen)) (human-Macaca irus monoclonal IDEC-114 heavy chain), disulfide with human- Macaca irus monoclonal IDEC-114 l chain, dimer
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
coreceptor activity; protein binding; receptor activity;