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altumomab pentetate (TAB-H03)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CEA Therapeutic Antibody (Hybri-ceaker) TAB-H03 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse antibody to Human CEA. Indium (111In) altumomab pentetate (INN) (USP, indium In 111 altumomab pentetate; trade name Hybri-ceaker) is a mouse monoclonal antibody linked to pentetate which acts as a chelating agent for the radioisotope indium-111. The drug is used for the diagnosis of colorectal cancer
  • Type
  • IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
  • CAS
  • 156586-92-4
  • Trade name
  • hybri-ceaker
  • Protein Construction
  • Indium (111In) labeled
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.

BACKGROUND

  • Introduction
  • Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
  • Keywords
  • CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; BGP1; BGPI; antigen CD66; CD66a antigen; CEACAM3; carcinoembryonic antigen-related cell adhesion molecule 3; CEA; CGM1; Carcinoembryonic antigen

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