lenzilumab

Cat

TAB-H44

Product Overview

Recombinant human antibody to Human CSF2

Type

IgG1 - kappa

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.

CAS

1229575-09-0

Specificity

CSF2 (colony stimulating factor 2 (granulocyte-macrophage), granulocyte-macrophage colony stimulating factor, GM-CSF) [Homo sapiens]

Protein Construction

gamma1 heavy chain (1-449) [Homo sapiens VH (IGHV1-3*01 (94.90%) – (IGHD) – IGHJ4*01) [8.8.12] (1-119) – IGHG1*03 (CH1 (120-217), hinge(218-232), CH2 (233-342), CH3 (343-447), CHS (448-449)) (120-449)], (222-214') – disulfide withkappa light chain (1'-214') [Homo sapiens V-KAPPA (IGKV3-20*01 (85.40%) -IGKJ4*01) [6.3.9] (1'-107') -IGKC*01 (108'-214')]; dimer (228-228'':231-231'') – bisdisulfide

Purity

>95.0% as determined by analysis by SDS-PAGE.

Antigen Description

General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.

Function

cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity; protein binding;

Gene ID

1437

Synonyms

CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897;

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