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Demcizumab (TAB-204)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human DLL4 Therapeutic Antibody TAB-204 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to DLL4. Demcizumab is a humanized monoclonal antibody designed for the treatment of cancer.
  • Target
  • DLL4
  • Type
  • IgG2 - kappa
  • Immunogen
  • Partial recombinant DLL4 ragment.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
  • CAS
  • 1243262-17-0
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G2-kappa, anti-[Homo sapiens DLL4 (delta-like 4)], humanized monoclonal antibody; gamma2 heavy chain (1-444) disulfide with kappa light chain (1"-218") dimer.
  • Predicted N terminal
  • H chain: QVQLVQS; L chain: DIVMTQS
  • Molecular Weight
  • 145300
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
  • Function
  • Notch binding; calcium ion binding;
  • Synonyms
  • DLL4; delta-like 4 (Drosophila); delta like 4 homolog (Drosophila); delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4; hdelta2; MGC126344;

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