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Rilotumumab (TAB-080)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human HGF Therapeutic Antibody TAB-080 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody Fragment Fab to HGF. Rilotumumab is a human monoclonal antibody designed for the treatment of solid tumors.
  • Target
  • HGF
  • Type
  • IgG2 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
  • CAS
  • 872514-65-3
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G2, anti-(human hepatocyte growth factor) (human monoclonal 2.12.1 heavy chain), disulfide with human monoclonal 2.12.1 light chain, dimer
  • Predicted N terminal
  • H Chain: QVQLQES; L Chain: EIVMTQS
  • Molecular Weight
  • 145200
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
  • Function
  • catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;
  • Synonyms
  • HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39;

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