Flanvotumab

Cat

TAB-130

Product Overview

Recombinant monoclonal antibody to HGF. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.

Target

HGF

Type

IgG1 - kappa

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.

CAS

1188277-05-5

Specificity

Tested positive against native human antigen.

Protein Construction

Immunoglobulin G1, anti-(human glycoprotein gp75) (human monoclonal IMC-20D7S heavy chain), disulfide with human monoclonal IMC-20D7S light chain, dimer

Predicted N terminal

H chain: QVQLVQS; L chain: EIVLTQS

Molecular Weight

145543

Purity

>95.0% as determined by analysis by SDS-PAGE.

Size

1mg

Storage

Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Antigen Description

HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.

Function

catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;

Gene ID

3082

Synonyms

HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39;

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