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Recombinant monoclonal antibody to HGF. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.
IgG1 - kappa
The details of the immunogen for this antibody are not available.
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
Tested positive against native human antigen.
Immunoglobulin G1, anti-(human glycoprotein gp75) (human monoclonal IMC-20D7S heavy chain), disulfide with human monoclonal IMC-20D7S light chain, dimer
Predicted N terminal
H chain: QVQLVQS; L chain: EIVLTQS
>95.0% as determined by analysis by SDS-PAGE.
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;