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Enlimomab pegol (TAB-241)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ICAM-1 Therapeutic Antibody Fab fragment TAB-241 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody Fab to ICAM-1.
  • Target
  • ICAM-1
  • Type
  • Fab' - G2a
  • Immunogen
  • Tissue / cell preparation (Human). (Burkitt"s lymphoma cell line RAJI).
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
  • CAS
  • 169802-84-0
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G 2a (human monoclonal BI-RR-1 anti-human antigen CD 54), disulfide with mouse monoclonal BI-RR-1 light chain, dimer, reaction product with alpha-(2-carboxyethyl)-ω-methoxypoly(oxy-1,2-ethanediyl)
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • Function
  • cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;

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