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Teprotumumab (TAB-151)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IGF1 Therapeutic Antibody TAB-151 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IGF1. Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease. A phase I clinical trial has been conducted in 2006/07. Gantenerumab is currently being evaluated in a prodromal Alzheimer's Disease population in the Scarlet Road study, a global phase II study of approximately 360 subjects in 100 centers in 15 countries.
  • Target
  • IGF1
  • Type
  • IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • CAS
  • 89957-37-9
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human beta-amyloid proteins 42 and 40) human monoclonal antibody
  • Predicted N terminal
  • H chain: QVELVES; L chain: EIVLTQS
  • Molecular Weight
  • 145600
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
  • Function
  • growth factor activity; hormone activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; integrin binding; protein binding;
  • Synonyms
  • IGF1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; IGF1A; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; IGFI; IGF-I;

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