Close

Anti-CXCL8 Protein A Scaffold (AFB-34LY)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL-8 Protein A scaffold AFB-34LY 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • The Anti-IL-8 Protein A Scaffold molecule was selected against human recombinant IL-8. Cross reactivity with other species has not been tested. The Anti-IL-8 Protein A Scaffold molecule is an ideal affinity ligand as capture reagent in ELISA. The Anti-IL-8 Protein A Scaffold molecule is modified with a unique C-terminal cysteine for directed single-point chemical modification, facilitating labeling with fluorescent dyes, biotin or coupling to matrices.
  • Species Reactivity
  • human
  • Expression Host
  • E. coli
  • Applications
  • ELISA
  • Specific Activity
  • Anti-IL-8 Protein A scaffold molecule binds to human IL-8. Cross reactivity with other species has not been tested.
  • Molecular Weight
  • 13.8 kDa
  • Storage
  • At +4°C is recommended for lyophilized protein. For reconstituted protein in physiological buffer, short-term storage at +4°C is recommended. For long-term storage, the protein solution should first be aliquoted and stored frozen at -20°C.
    There is no dec

BACKGROUND

  • Antigen Description
  • Interleukin 8 (IL-8) or CXCL8 is a non-glycosylated protein of 8 kDa belonging to the CXC family of chemokines. IL-8 is produced as a precursor protein of 99 amino acids and processing of the precursor results in variants of IL-8 that have various biological effects. It is produced by a number of cell types in response to inflammatory stimuli such as LPS, TNF and viruses. The IL-8 receptor belongs to the G-protein coupled receptor family and is expressed on many cell types including neutrophilic granulocytes. The role of IL-8 is primarily to attract neutrophilic granulocytes to the site of inflammation upon binding to the receptor. IL-8 causes a transient increase in cytosolic calcium levels, the release of enzymes from granules as well as enhanced expression of adhesion molecules in neutrophils.
  • Function
  • chemokine activity; interleukin-8 receptor binding; protein binding.
  • Synonyms
  • CXCL8; chemokine (C-X-C motif) ligand 8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; interleukin-8; emoctakin; interleukin 8; T-cell chemotactic factor; neutrophil-activating peptide 1; beta-thromboglobulin-like protein; granulocy

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us