Lebrikizumab

Cat

TAB-219

Product Overview

Recombinant monoclonal antibody to IL13. Lebrikizumab (INN) is a humanized monoclonal antibody and an experimental immunosuppresive drug for the treatment of asthma that cannot be adequately controlled with inhalable glucocorticoids.

Target

IL13

Type

IgG4 - kappa

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.

Specificity

Tested positive against native human antigen.

Protein Construction

Immunoglobulin G4-kappa, anti-[Homo sapiens interleukin 13 (IL13,IL-13)], humanized monoclonal antibody

Predicted N terminal

H chain: QVTLRES; L chain: DIVMTQS

Molecular Weight

145285

Purity

>95%, by SDS-PAGE with silver staining, under reducing conditions.

Size

1mg

Storage

Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Antigen Description

Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.

Function

cytokine activity; interleukin-13 receptor binding; protein binding;

Gene ID

3596

Synonyms

IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;

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