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Recombinant Humanized (from mouse) antibody to Human IL13. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
Type
IgG1
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods.
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
BACKGROUND
Antigen Description
Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure.
Function
cytokine activity; interleukin-13 receptor binding; protein binding;