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anrukinzumab (TAB-H05)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL13 Therapeutic Antibody TAB-H05 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) antibody to Human IL13. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
  • Type
  • IgG1
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods.
  • CAS
  • 910649-32-0
  • Specificity
  • IL13 (interleukin 13, IL-13) [Homo sapiens]
  • Protein Construction
  • gamma1 heavy chain [humanized VH (Homo sapiens FR/Mus musculus CDR) [8.7.12] -Homo sapiens IGHG1*03, 97R>K (CH1 120), 117L>A (CH2 1.3),120G>A (CH2 1] (221-218')-disulfide withkappa light chain [humanized V-KAPPA (Homo sapiens FR/Mus musculus CDR) [10.3.9] -Homo sapiens IGKC*01]; (227-227'':230-230'')-bisdisulfidedimer
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.

BACKGROUND

  • Antigen Description
  • Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure.
  • Function
  • cytokine activity; interleukin-13 receptor binding; protein binding;
  • Synonyms
  • IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;

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