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Secukinumab (TAB-069)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL17A Therapeutic Antibody TAB-069 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IL17A. Secukinumab is a human monoclonal antibody designed for the treatments of uveitis, rheumatoid arthritis, and psoriasis. It targets member A from the cytokine family of interleukin 17.
  • Target
  • IL17A
  • Type
  • IgG1 - kappa
  • Immunogen
  • HuIL-17 coupled 10 KLH mixed 1:1 with huIL-17 in Gerbu adjuvant.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 875356-43-7
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human interleukin-17A (IL-17, cytotoxic T-lymphocyte-associated antigen 8)); human monoclonal AIN457 γ1 heavy chain (230-215")-disulfide with human monoclonal AIN457 kappa light chain dimer
  • Predicted N terminal
  • H Chain: EVQLVES; L Chain: EIVLTQS
  • Molecular Weight
  • 147940
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.
  • Function
  • cytokine activity;
  • Synonyms
  • IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); IL17; CTLA8; IL-17; IL-17A;

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