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Pascolizumab (TAB-221)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL4 Therapeutic Antibody TAB-221 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IL4. Pascolizumab is a humanized monoclonal antibody for the treatment of asthma.
  • Target
  • IL4
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
  • CAS
  • 331243-22-2
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human interleukin 4) (human-mouse monoclonal SB-240683 g1-chain), disulfide with human-mouse monoclonal SB-240683 k-chain, dimer
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
  • Function
  • cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding;
  • Synonyms
  • IL4; interleukin 4; interleukin-4; B cell growth factor 1; B_cell stimulatory factor 1; BCGF 1; BCGF1; BSF1; IL 4; lymphocyte stimulatory factor 1; MGC79402; binetrakin; pitrakinra; IL-4; BSF-1; BCGF-1;

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