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Igovomab (TAB-043)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human MUC16 Therapeutic Antibody F(ab')2 fragment (Indimacis-125) TAB-043 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant antibody F(ab')2 fragment Fabto MUC16. Indium (111In) igovomab (trade name Indimacis-125) was a mouse monoclonal antibody for the diagnosis of ovarian cancer.
    Linked to the chelating agent DTPA and labelled with Indium-111, it was used for imaging (radio-immuno scintigraphy) of the cancer. The drug is no longer available.
  • Target
  • MUC16
  • Type
  • F(ab')2 - G1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, IHC and most other immunological methods.
  • CAS
  • 171656-50-1
  • Trade name
  • indimacis-125
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1,anti-(human carcinoembryonic antigen) (mouse monoclonal ZCE025 g1-chain), disulfide with mousemonoclonal ZCE025 light chain, dimer
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Size
  • 1mg
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
  • Function
  • protein binding;
  • Synonyms
  • MUC16; mucin 16, cell surface associated; mucin-16; CA125; FLJ14303; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125;

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