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Onartuzumab (TAB-190-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Met(c-Met) therapeutic Antibody Fab Fragment TAB-190-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody Fragment Fab to Met. Onartuzumab is a humanized monoclonal antibody designed for the treatment of cancer.
  • Target
  • Met(c-Met)
  • Type
  • Fab / Fc - G1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • CAS
  • 1133766-06-9
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human scatter factor receptor kinase)(human-mouse monoclonal MetMAb heavy chain), disulfide with human-mouse monoclonal MetMAb kappa-chain, disulfide with human-mouse monoclonal MetMAb heavy chain hinge region-CH2-CH3 domain-containing fragment
  • Predicted N terminal
  • H chain: EVQLVES; L chain: DIQMTQS
  • Molecular Weight
  • 99146
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
  • Function
  • ATP binding; hepatocyte growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor activity;
  • Synonyms
  • MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met;

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