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Indium (111In) imciromab (TAB-H42)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Myosin Therapeutic Antibody (MYOSCINT) TAB-H42 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse antibody to Human Myosin. Indium (111In) imciromab (trade name Myoscint) is a mouse monoclonal antibody labelled with the radioisotopeIndium-111. It was used for cardiac imaging.
  • Type
  • Fab - G2a - kappa
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
  • CAS
  • 126132-83-0
  • Trade name
  • myoscint
  • Specificity
  • myosin, cardiac [Homo sapiens]
  • Protein Construction
  • Myoscint is a murine monoclonal antibody Fab fragment bound to DTPA (diethylenetriaminepentaacetic acid) that is radiolabeled with indium-111for cardiac imaging performed with a nuclear medicine gamma camera employing either planar or tomographic techniques. Myoscint binds withhigh affinity and specificity to myosin, a protein exposed in necrotic myocardial cells.
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.

BACKGROUND

  • Introduction
  • Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in striated and smooth muscle cells.
  • Keywords
  • Myosin; Myosins cardiac myosin

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