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Recombinant Mouse antibody to Human Myosin. Indium (111In) imciromab (trade name Myoscint) is a mouse monoclonal antibody labelled with the radioisotopeIndium-111. It was used for cardiac imaging.
Fab - G2a - kappa
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
myosin, cardiac [Homo sapiens]
Myoscint is a murine monoclonal antibody Fab fragment bound to DTPA (diethylenetriaminepentaacetic acid) that is radiolabeled with indium-111for cardiac imaging performed with a nuclear medicine gamma camera employing either planar or tomographic techniques. Myoscint binds withhigh affinity and specificity to myosin, a protein exposed in necrotic myocardial cells.
>95.0% as determined by analysis by RP-HPLC.
Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in striated and smooth muscle cells.