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Pidilizumab (TAB-900)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human PD-1/PDCD1/CD279 Therapeutic Antibody TAB-900 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized (from mouse) antibody expressed in CHO binding to human PD-1. Pidilizumab is a monoclonal antibody designed for the treatment of cancer and infectious diseases.
  • Target
  • PD-1
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
  • CAS
  • 1310680-64-8
  • Molecular Weight
  • 147.43 kDa
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Introduction
  • Pidilizumab is a monoclonal antibody designed for the treatment of cancer and infectious diseases.
  • Antigen Description
  • Possible cell death inducer, in association with other factors. Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • Function
  • protein binding; protein tyrosine phosphatase activity; signal transducer activity;
  • Synonyms
  • PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l;

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